New Surgical Technologies : iKnife (Intelligent Surgical Knife)

iKnife (Intelligent Surgical Knife)
(also known as the Onkoknife or intelligent scalpel)

The principle technology behind this tool is called Rapid Evaporative Ionisation Mass Spectrometry (REIMS).

This technology was invented by Dr Zoltan Takats of Imperial College London. He realised that the smoke generated during electrodissection would be a rich source of biological information. He connected the electrosurgical knife to a mass spectrometer, an analytical instrument used to identify what chemicals are present in a sample.

iKnife allows near–real-time characterization of human tissue in vivo by analysis of the aerosol (“smoke”) released during electrosurgical dissection.


To establish the proof of concept a study was conducted where a variety of tissue samples from 302 patients were analyzed in the laboratory, resulting in 1624 cancerous and 1309 noncancerous database entries. Continue Reading About iKnife Here.

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